Research news

In HD, a key brain protector, PKD1, is missing. Without this “molecular firefighter,” neurons are vulnerable. Knowing why it disappears may help us uncover how the brain’s defense break down, and how to reinforce it.

Spark and Roche issued a joint community letter to share that the first patient has been dosed in a new HD gene therapy trial.

Each person with HD has genetic spelling changes that can impact HD symptoms. Scientists have released the latest in a series of genetic studies examining these spelling changes, shining a light on new paths to develop treatments for HD.